The Association of Psychological Comorbidity with the Number of Functional Gastrointestinal Disorders
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Methods: A total of 4763 individuals in 20 cities across Isfahan Province, Iran, were selected through cluster random sampling. The Rome III questionnaire in its complete form was used to investigate gastrointestinal symptoms. The other data collection tools consisted of the Stressful Life Events (SLE) Questionnaire, and Hospital Anxiety and Depression Scale (HADS). To analyze the data, t-test, chi-square test, and logistic regression analyses were used.
Results: The results of logistic regression analysis showed that the number of functional gastrointestinal disorders was the risk factor for stress level, anxiety, and depression and increased the odds ratio (OR) of these disturbances.
Conclusion: Increase in the number of functional gastrointestinal disorders was associated with more psychological comorbidity. Therefore, overlap of functional gastrointestinal disorders functional gastrointestinal disorders to be carefully considered and physicians should pay more attention to psychological factors when FGIDs overlap.
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Adibi, P., Keshteli, A. H., Esmaillzadeh, A., Afshar, H., Roohafza, H., Bagherian-Sararoudi, R. et al. (2012). The study on the epidemiology of psychological, alimentary health and nutrition (SEPAHAN): Overview of methodology. J Res Med Sci, 17(Spec 2), S291-S297.
Attanasio, V., Andrasik, F., Blanchard, E. B., & Arena, J. G. (1984). Psychometric properties of the SUNYA revision of the Psychosomatic Symptom Checklist. J Behav Med, 7(2), 247-257. Retrieved from PM:6748072
Bennett, E. J., Piesse, C., Palmer, K., Badcock, C. A., Tennant, C. C., & Kellow, J. E. (1998). Functional gastrointestinal disorders: psychological, social, and somatic features. Gut, 42(3), 414-420. Retrieved from PM:9577351
Bouchoucha, M., Hejnar, M., Devroede, G., Babba, T., Bon, C., & Benamouzig, R. (2013). Anxiety and depression as markers of multiplicity of sites of functional gastrointestinal disorders: a gender issue? Clin Res Hepatol.Gastroenterol, 37(4), 422-430. doi:S2210-7401(12)00330-0 [pii];10.1016/j.clinre.2012.10.011 [doi]. Retrieved from PM:23270854
Choung, R. S., Chang, J. Y., Locke, G. R., Schleck, C. D., Zinsmeister, A. R., & Talley, N. J. (2011). Is Having Multiple Functional Gastrointestinal Disorders Distinct From Having a Single FGID? A Population Based Study. Gastroenterology, 140(5), S-708.
Dalton, C. Ask the expert. Question: What is a Functional GI disorder? UNC Center for Functional GI and Motility Disorders. Available from: URL: https://www.med.unc.edu/ibs/files/educational-gi-handouts/ What%20Is%20Functional%20GI.pdf. Accessed 2014.
Dobrek, L., & Thor, P. J. (2009). Pathophysiological concepts of functional dyspepsia and irritable bowel syndrome future pharmacotherapy. Acta Pol. Pharm, 66(5), 447-460. Retrieved from PM:19894640
Drossman, D. A., Corazziari, E., Delvaux, M, Spiller, R. C., Talley, N. J., Thompson, W. G. et al (2006). Rome III: The functional gastrointestinal disorders, 3rd ed. McLean, VA: Degnon.
Drossman, D. A., Li, Z., Andruzzi, E., Temple, R. D., Talley, N. J., Thompson, W. G. et al. (1993). U.S. householder survey of functional gastrointestinal disorders. Prevalence, sociodemography, and health impact. Dig. Dis Sci, 38(9), 1569-1580. Retrieved from PM:8359066
Haug, T. T., Mykletun, A., & Dahl, A. A. (2002). Are anxiety and depression related to gastrointestinal symptoms in the general population? Scand. J Gastroenterol, 37(3), 294-298. Retrieved from PM:11916191
Jones, M. P., Crowell, M. D., Olden, K. W., & Creed, F. (2007). Functional gastrointestinal disorders: an update for the psychiatrist. Psychosomatics, 48(2), 93-102. doi:48/2/93 [pii];10.1176/appi.psy.48.2.93 [doi]. Retrieved from PM:17329601
Kaji, M., Fujiwara, Y., Shiba, M., Kohata, Y., Yamagami, H., Tanigawa, T. et al. (2010). Prevalence of overlaps between GERD, FD and IBS and impact on health-related quality of life. J Gastroenterol Hepatol., 25(6), 1151-1156. doi:JGH6249 [pii];10.1111/j.1440-1746.2010.06249.x [doi]. Retrieved from PM:20594232
Koloski, N. A., Talley, N. J., & Boyce, P. M. (2002). Epidemiology and health care seeking in the functional GI disorders: a population-based study. Am J Gastroenterol, 97(9), 2290-2299. doi:10.1111/j.1572-0241.2002.05783.x [doi]. Retrieved from PM:12358247
Koloski, N. A., Jones, M., Kalantar, J., Weltman, M., Zaguirre, J., & Talley, N. J. (2012). The brain--gut pathway in functional gastrointestinal disorders is bidirectional: a 12-year prospective population-based study. Gut, 61(9), 1284-1290. doi:gutjnl-2011-300474 [pii];10.1136/gutjnl-2011-300474 [doi]. Retrieved from PM:22234979
Lee, H. J., Lee, S. Y., Kim, J. H., Sung, I. K., Park, H. S., Jin, C. J. et al. (2010). Depressive mood and quality of life in functional gastrointestinal disorders: differences between functional dyspepsia, irritable bowel syndrome and overlap syndrome. Gen.Hosp Psychiatry, 32(5), 499-502. doi:S0163-8343(10)00103-9 [pii];10.1016/j.genhosppsych.2010.05.002 [doi]. Retrieved from PM:20851270
Mikocka-Walus, A. A., Turnbull, D. A., Andrews, J. M., Moulding, N. T., & Holtmann, G. J. (2008). The effect of functional gastrointestinal disorders on psychological comorbidity and quality of life in patients with inflammatory bowel disease. Aliment Pharmacol Ther, 28(4), 475-483. doi:APT3754 [pii];10.1111/j.1365-2036.2008.03754.x [doi]. Retrieved from PM:18532989
Park, J. M., Choi, M. G., Cho, Y. K., Lee, I. S., Kim, J. I., Kim, S. W. et al. (2011). Functional Gastrointestinal Disorders Diagnosed by Rome III Questionnaire in Korea. J Neurogastroenterol.Motil., 17(3), 279-286. doi:10.5056/jnm.2011.17.3.279 [doi]. Retrieved from PM:21860820
Park, J. W., Cho, Y. S., Lee, S. Y., Kim, E. S., Cho, H., Shin, H. E. et al. (2013). Concomitant functional gastrointestinal symptoms influence psychological status in Korean migraine patients. Gut Liver, 7(6), 668-674. doi:10.5009/gnl.2013.7.6.668 [doi]. Retrieved from PM:24312707
Roohafza, H., Ramezani, M., Sadeghi, M., Shahnam, M., Zolfagari, B., & Sarafzadegan, N. (2011). Development and validation of the stressful life event questionnaire. Int J Public Health, 56(4), 441-448. doi:10.1007/s00038-011-0232-1 [doi]. Retrieved from PM:21327856
Sali, R., Roohafza, H., Sadeghi, M., Andalib, E., Shavandi, H., & Sarrafzadegan, N. (2013). Validation of the revised stressful life event questionnaire using a hybrid model of genetic algorithm and artificial neural networks. Comput Math Methods Med, 2013, 601640. doi:10.1155/2013/601640 [doi]. Retrieved from PM:23476715
Snaith, R. P. (2003). The Hospital Anxiety and Depression Scale. Health Qual Life Outcomes, 1, 29.
Suzuki, H., & Hibi, T. (2011). Overlap syndrome of functional dyspepsia and irritable bowel syndrome - are both diseases mutually exclusive? J Neurogastroenterol. Motil., 17(4), 360-365. doi:10.5056/jnm.2011.17.4.360 [doi]. Retrieved from PM:22148104
Van, Oudenhove, L., Vandenberghe, J., Geeraerts, B., Vos, R., Persoons, P., Fischler, B. et al. (2008). Determinants of symptoms in functional dyspepsia: gastric sensorimotor function, psychosocial factors or somatisation? Gut, 57(12), 1666-1673. doi:gut.2008.158162 [pii];10.1136/gut.2008.158162 [doi]. Retrieved from PM:18625692
Van, Oudenhove, L., Vandenberghe, J., Demyttenaere, K., & Tack, J. (2010). Psychosocial factors, psychiatric illness and functional gastrointestinal disorders: a historical perspective. Digestion, 82(4), 201-210. doi:000269822 [pii];10.1159/000269822 [doi]. Retrieved from PM:20588034
Walker, E. A., Roy-Byrne, P. P., Katon, W. J., Li, L., Amos, D., & Jiranek, G. (1990). Psychiatric illness and irritable bowel syndrome: a comparison with inflammatory bowel disease. Am J Psychiatry, 147(12), 1656-1661. doi:10.1176/ajp.147.12.1656 [doi]. Retrieved from PM:2103735
Wang, A., Liao, X., Xiong, L., Peng, S., Xiao, Y., Liu, S. et al. (2008). The clinical overlap between functional dyspepsia and irritable bowel syndrome based on Rome III criteria. BMC Gastroenterol, 8 , 43. doi:1471-230X-8-43 [pii];10.1186/1471-230X-8-43 [doi]. Retrieved from PM:18808723
Wu, J. C. (2012). Psychological Co-morbidity in Functional Gastrointestinal Disorders: Epidemiology, Mechanisms and Management. J Neurogastroenterol. Motil., 18(1), 13-18. doi:10.5056/jnm.2012.18.1.13 [doi]. Retrieved from PM:22323984
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