The Effectiveness of Acceptance and Commitment Therapy on Perceived Stress and Health Anxiety in Women with Breast Cancer
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Objective: Cancer, as a chronic physical illness, disrupts both the physical and psychological capacities of individuals, creating a distressing condition for the patient that diminishes quality of life, deteriorates mental health, and reduces overall well-being. This study aimed to evaluate the effectiveness of Acceptance and Commitment Therapy (ACT) on perceived stress and health anxiety in women diagnosed with breast cancer.
Methods and Materials: This quasi-experimental study employed a non-equivalent control group design with pre-test, post-test, and follow-up stages. A purposive sample of 30 women with breast cancer (aged 20–45) referred to medical centers in Tehran in 2023 was selected. Participants were randomly assigned to an ACT intervention group or a control group (n=15). The intervention group received ten 90-minute ACT sessions based on Hayes et al.’s (2004) protocol. Data were collected using the Perceived Stress Scale (PSS-14) and Health Anxiety Inventory (HAI). Repeated measures ANOVA was used for statistical analysis.
Findings: Findings revealed a significant reduction in perceived stress and health anxiety in the ACT group compared to the control group at both post-test and follow-up stages (p<0.001). Effect sizes indicated strong practical significance across all variables.
Conclusion: ACT appears to be an effective intervention for improving psychological well-being in women with breast cancer by reducing stress-related symptoms. These findings support the integration of ACT into supportive care for breast cancer patients.
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Abramowitz, J. S., Olatunji, B. O., & Deacon, B. J. (2007). Health anxiety, hypochondriasis, and the anxiety disorders. Behavior therapy, 38(1), 86-94. https://doi.org/10.1016/j.beth.2006.05.001
Albahadlv, W. K. Y., Mohammed, A. H., Sabti, A. A., Al-Hili, A., Adnan, M., & Sabri, S. K. (2023). The Effectiveness of Mindfulness-Based Stress Reduction on Stress, Anxiety, and Depression of Patients with Breast Cancer. International Journal of Body, Mind & Culture (2345-5802), 10(1).https:// 10.22122/ijbmc.v10i1.426
Andreevich, S. M., Jumaa, H. J., Sadeq, S. S., Jawad, I. A., Altememy, H. A., Jabbar, A. M., Majeed, M. A., Mohammed, W. K., & Nasser, H. A. (2023). Evaluating the Effect of Acceptance and Commitment Therapy on Anxiety and Quality of Life in Stomach Cancer Patients. International Journal of Body, Mind & Culture (2345-5802), 10(4). https://10.22122/ijbmc.v10i4.579
Barbek, R. M., Makowski, A. C., & von dem Knesebeck, O. (2022). Social inequalities in health anxiety: A systematic review and meta-analysis. Journal of psychosomatic research, 153, 110706. https://doi.org/10.1016/j.jpsychores.2021.110706
Bareket-Bojmel, L., Shahar, G., & Margalit, M. (2021). COVID-19-related economic anxiety is as high as health anxiety: findings from the USA, the UK, and Israel. International journal of cognitive therapy, 14(3), 566-574. https://doi.org/10.1007/s41811-020-00078-3
Callaghan, G. M., Duenas, J. A., Nadeau, S. E., Darrow, S. M., Van der Merwe, J., & Misko, J. (2012). An empirical model of body image disturbance using behavioral principles found in Functional Analytic Psychotherapy and Acceptance and Commitment Therapy. International Journal of Behavioral Consultation and Therapy, 7(2-3), 16. https://doi.org/10.1037/h0100932
Carr, A., Cullen, K., Keeney, C., Canning, C., Mooney, O., Chinseallaigh, E., & O’Dowd, A. (2021). Effectiveness of positive psychology interventions: a systematic review and meta-analysis. The journal of positive psychology, 16(6), 749-769. https://doi.org/10.1080/17439760.2020.1818807
Cohen, A. N., Hammen, C., Henry, R. M., & Daley, S. E. (2004). Effects of stress and social support on recurrence in bipolar disorder. Journal of affective disorders, 82(1), 143-147. https://doi.org/10.1016/j.jad.2003.10.008
DaneshNia, F. (2023). The Difference Between the Effectiveness of Self-Care Training and Mindfulness-Based Stress Reduction Therapy on The Health-Related Quality of Life of Patients with Rheumatoid Arthritis. Iranian Journal of Positive Psychology, 9(1), 1-5. https://www.academia.edu/97437583/The_Difference_Between_the_Effectiveness_of_Self_Care_Training_and_Mindfulness_Based_Stress_Reduction_Therapy_on_The_Health_Related_Quality_of_Life_of_Patients_with_Rheumatoid_Arthritis
Davoudi-Monfared, E., Radfar, S., Mohseny, M., & Hosseini-Dastjerdi, Z. S. (2023). The Relationship between Coping Strategies and Quality of Life in Women with Breast Cancer. International Journal of Body, Mind & Culture (2345-5802), 10(2).https://10.22122/ijbmc.v10i2.402
Dennis, D., Radnitz, C., & Wheaton, M. G. (2021). A perfect storm? Health anxiety, contamination fears, and COVID-19: lessons learned from past pandemics and current challenges. International journal of cognitive therapy, 14(3), 497-513. https://doi.org/10.1007/s41811-021-00109-7
https://doi.org/10.1007/s41811-021-00110-0
Drigas, A., Mitsea, E., & Skianis, C. (2022). Neuro-linguistic programming, positive psychology & VR in special education. Scientific Electronic Archives, 15(1). https://doi.org/10.36560/15120221497
Fernández-Rodríguez, C., González-Fernández, S., Coto-Lesmes, R., & Pedrosa, I. (2021). RETRACTED: Behavioral Activation and Acceptance and Commitment Therapy in the Treatment of Anxiety and Depression in Cancer Survivors: A Randomized Clinical Trial. Behavior modification, 45(5), 822-859. https://doi.org/10.1177/0145445520916441
Han, A., Yuen, H. K., & Jenkins, J. (2021). Acceptance and commitment therapy for family caregivers: A systematic review and meta-analysis. Journal of Health Psychology, 26(1), 82-102. https://doi.org/10.1177/1359105320941217
Hayes, S. C., Strosahl, K. D., & Strosahl, K. (2004). A practical guide to acceptance and commitment therapy. Springer Science & Business Media. https://doi.org/10.1007/978-0-387-23369-7
Jan, F., Singh, M., & Nisar, S. (2021). Perceived stress in cancer patients: An integrative review. Indian Journal of Psychiatric Nursing, 18(2), 113-125. https://doi.org/10.4103/iopn.iopn_4_21
Jawad, M. A., Abulkassim, R., Mohameed, D. A. A.-H., Razak, T. A., & Al-Baghdady, H. a. F. A. (2022). The Effectiveness of Acceptance and Commitment Therapy on Physical Health and Quality of Life in Patients with Gastric (Stomach) Cancer. International Journal of Body, Mind & Culture (2345-5802), 9.https://10.22122/ijbmc.v9isp.419
Kashyap, D., Pal, D., Sharma, R., Garg, V. K., Goel, N., Koundal, D., Zaguia, A., Koundal, S., & Belay, A. (2022). [Retracted] Global increase in breast cancer incidence: risk factors and preventive measures. BioMed research international, 2022(1), 9605439. https://doi.org/10.1155/2022/9605439
Katsura, C. (2022). Ogunmwonyi I. Kankam HK Saha S. Breast cancer: presentation, investigation and management. Br. J. Hosp. Med, 83(2), 1. https://doi.org/10.12968/hmed.2021.0459
Li, J., Gao, W., Yang, Q., & Cao, F. (2021). Perceived stress, anxiety, and depression in treatment‐naïve women with breast cancer: a case‐control study. Psycho‐Oncology, 30(2), 231-239. https://doi.org/10.1002/pon.5555
Mahdavi, A., Aghaei, M., Aminnasab, V., Tavakoli, Z., Besharat, M., & Abedin, M. (2017). The effectiveness of acceptance-commitment therapy (ACT) on perceived stress, symptoms of depression, and marital satisfaction in women with breast cancer. Archives of Breast Cancer, 16-23. https://doi.org/10.19187/abc.20174116-23
Maheu, C., Singh, M., Tock, W. L., Eyrenci, A., Galica, J., Hébert, M., Frati, F., & Estapé, T. (2021). Fear of cancer recurrence, health anxiety, worry, and uncertainty: A scoping review about their conceptualization and measurement within breast cancer survivorship research. Frontiers in psychology, 12, 644932. https://doi.org/10.3389/fpsyg.2021.644932
Mimura, C., & Griffiths, P. (2004). A Japanese version of the perceived stress scale: translation and preliminary test. International journal of nursing studies, 41(4), 379-385. https://doi.org/10.3389/fpsyg.2021.644932
Nargesi, F., Izadi, F., Kariminejad, K., & REZAII, S. A. (2017). The investigation of the reliability and validity of Persian version of Health anxiety questionnaire in students of Lorestan University of Medical Sciences. https://sid.ir/paper/214567/en
Nikčević, A. V., Marino, C., Kolubinski, D. C., Leach, D., & Spada, M. M. (2021). Modelling the contribution of the Big Five personality traits, health anxiety, and COVID-19 psychological distress to generalised anxiety and depressive symptoms during the COVID-19 pandemic. Journal of affective disorders, 279, 578-584. https://doi.org/10.1016/j.jad.2020.10.053
Park, M., Kim, D., Ko, S., Kim, A., Mo, K., & Yoon, H. (2022). Breast cancer metastasis: mechanisms and therapeutic implications. International journal of molecular sciences, 23(12), 6806. https://doi.org/10.3390/ijms23126806
Plascak, J. J., Llanos, A. A., Mooney, S. J., Rundle, A. G., Qin, B., Lin, Y., Pawlish, K. S., Hong, C.-C., Demissie, K., & Bandera, E. V. (2021). Pathways between objective and perceived neighborhood factors among Black breast cancer survivors. BMC public health, 21(1), 2031. https://doi.org/10.1186/s12889-021-12057-0
Ramirez, A. G., Muñoz, E., Long Parma, D., Perez, A., & Santillan, A. (2020). Quality of life outcomes from a randomized controlled trial of patient navigation in Latina breast cancer survivors. Cancer medicine, 9(21), 7837-7848. https://doi.org/10.1002/cam4.3272
Sadeghpour, M., Farokhzad, P., Sarichlo, M. E., & Moghadam, H. E. (2025). Comparison of the Effectiveness of Acceptance and Commitment Therapy and Cognitive-Behavioral Therapy on Death Anxiety and Life Hope in Breast Cancer Patients. International Journal of Education and Cognitive Sciences, 6(1), 56-66. https://doi.org/10.61838/kman.ijecs.6.1.6
Salkovskis, P. M., Rimes, K. A., Warwick, H. M., & Clark, D. (2002). The Health Anxiety Inventory: development and validation of scales for the measurement of health anxiety and hypochondriasis. Psychological Medicine, 32(5), 843-853. https://doi.org/10.1017/S0033291702005822
Seshadri, A., Orth, S. S., Adaji, A., Singh, B., Clark, M. M., Frye, M. A., McGillivray, J., & Fuller-Tyszkiewicz, M. (2021). Mindfulness-based cognitive therapy, acceptance and commitment therapy, and positive psychotherapy for major depression. American journal of psychotherapy, 74(1), 4-12. https://doi.org/10.1176/appi.psychotherapy.20200006
Shi, C., Taylor, S., Witthöft, M., Du, X., Zhang, T., Lu, S., & Ren, Z. (2022). Attentional bias toward health-threat in health anxiety: a systematic review and three-level meta-analysis. Psychological Medicine, 52(4), 604-613. https://doi.org/10.1017/S0033291721005432
Sideris, N., Dama, P., Bayraktar, S., Stiff, T., & Castellano, L. (2022). LncRNAs in breast cancer: a link to future approaches. Cancer Gene Therapy, 29(12), 1866-1877. https://doi.org/10.1038/s41417-022-00487-w
Song, W., Shari, N. I., Song, J., Zhang, R., Mansor, N. S., Leong Bin Abdullah, M. F. I., & Zhang, Z. (2024). Effectiveness of Acceptance and Commitment Therapy (ACT) on disease acceptance for breast cancer patients: Study protocol of a randomized controlled trial. Plos one, 19(11), e0312669. https://doi.org/10.1038/s41417-022-00487-w
Tan, H., Plichta, J., Kong, A., Tan, C., Hwang, S., Sultana, R., Wright, M., Sia, A., Sng, B., & Habib, A. (2023). Risk factors for persistent pain after breast cancer surgery: a multicentre prospective cohort study. Anaesthesia, 78(4), 432-441. https://doi.org/10.1111/anae.15958
Thompson, E. M., Destree, L., Albertella, L., & Fontenelle, L. F. (2021). Internet-based acceptance and commitment therapy: a transdiagnostic systematic review and meta-analysis for mental health outcomes. Behavior therapy, 52(2), 492-507. https://doi.org/10.1016/j.beth.2020.07.002
Trindade, I. A., Guiomar, R., Carvalho, S. A., Duarte, J., Lapa, T., Menezes, P., Nogueira, M. R., Patrão, B., Pinto-Gouveia, J., & Castilho, P. (2021). Efficacy of online-based acceptance and commitment therapy for chronic pain: a systematic review and meta-analysis. The journal of pain, 22(11), 1328-1342. https://doi.org/10.1016/j.jpain.2021.04.003
Warwick, H. M., & Salkovskis, P. M. (1989). Cognitive and behavioural characteristics of primary hypochondriasis. Cognitive Behaviour Therapy, 18(2), 85-92. https://doi.org/10.1080/16506078909455848
Whelan, T. J., Smith, S., Parpia, S., Fyles, A. W., Bane, A., Liu, F.-F., Rakovitch, E., Chang, L., Stevens, C., & Bowen, J. (2023). Omitting radiotherapy after breast-conserving surgery in luminal a breast cancer. New England Journal of Medicine, 389(7), 612-619. https://doi.org/10.1056/NEJMoa2302344
Wilkinson, L., & Gathani, T. (2022). Understanding breast cancer as a global health concern. The British journal of radiology, 95(1130), 20211033. https://doi.org/10.1259/bjr.20211033
Zhang, J.-Y., Li, S.-S., Meng, L.-N., & Zhou, Y.-Q. (2022). Effectiveness of a nurse-led Mindfulness-based Tai Chi Chuan (MTCC) program on Posttraumatic Growth and perceived stress and anxiety of breast cancer survivors. European journal of psychotraumatology, 13(1), 2023314. https://doi.org/10.1080/20008198.2021.2023314
Zhao, C., Lai, L., Zhang, L., Cai, Z., Ren, Z., Shi, C., Luo, W., & Yan, Y. (2021). The effects of acceptance and commitment therapy on the psychological and physical outcomes among cancer patients: A meta-analysis with trial sequential analysis. Journal of psychosomatic research, 140, 110304. https://doi.org/10.1016/j.jpsychores.2020.110304
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