Effect of A Bioenergy Economy Program on Pain Control, Depression, and Anxiety In Patients with Migraine Headache

Master in Psychology, Department of Psychology, Isfahan Science and Research Branch, Islamic Azad University, Isfahan, Iran

Assistant Professor, Isfahan (Khorasgan) Branch, Islamic Azad University, Isfahan, Iran

Associate Professor, Psychosomatic Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Head of Danesh-e Tandorosti Institute, Isfahan, Iran AND Professor at Energy Medicine University, California, USA


Background: Psychological problems such as depression and anxiety are very common in patients with
chronic headaches and give rise to the repetition and continuity of the headaches. This study aimed to assess
the effect of a bioenergy economy program and particularly the biofield attunement on the improvement of the
pain control, depression, and anxiety in patients suffering from migraine, a common psychosomatic disorder.
Methods: To collect data, a quasi-experimental method was adopted including pretest, posttest, and
follow-up phase. Thirty patients with migraine were selected based on convenience sampling method and
put into two experimental and control groups. Data collection tools included Beck Depression Inventory-II
(BDI-II), Beck Anxiety Inventory, and Headache Impact Test (HIT-6TM). The data were analyzed using
repeated-measures analysis of variance (ANOVA) and covariance (ANCOVA) tests. Both experimental
and control groups participated in the entire program to assess the effect of bioenergy economy program
on mentioned variables. To assess the effect of biofield attunement, a non-expert person performed the
attunement of participants in the control group while an expert bioenergy healer and channel performed
attunement procedures for the participants in the experimental group.
Results: The mean scores of pain, anxiety, and depression of 30 participants in pretest differed
significantly with those in posttest and follow-up phases; but such a difference was not observed between
the scores of posttest and follow-up in control group. Moreover, the participants’ mean scores in posttest
and follow-up phases differed significantly between the two groups.
Conclusion: Bioenergy economy program caused a significant decrease in anxiety, depression, and
intensity and frequency of pain in patients with migraine. The decrease on mentioned variables were
consistent in a two-month interval. These therapeutic effects were even more in experimental group who
had received real biofield attunement. As bioenergy economy program and biofield attunement is a nonpharmaceutical
and harmless care system, it is recommended as an effective method for the reduction of
depression, anxiety, and pain in patients with migraine.


  • Migraine
  • Headache
  • Bioenergy economy
  • Biofield
  • Attunement
  • Pain
  • Depression
  • Anxiety

Full Text


Aminoff, M., Greenberg, D., & Simon, R. (2009).

Clinical Neurology (7th ed.). New York, NY: McGraw-

Hill Education.

Astin, J. (2000). Alternative therapies; Distance

healing: Evidence suggests patient may benefit.

Obesity, Fitness & Wellness Week.

Baginski, B. J., & Sharamon, S. (1997). Reiki:

Universal Life Energy: Holistic Method Suitable for

Self-Treatment and the Home Professional Practice,

Teleotherapeutics/Spiritual Healing. New York, NY:

New Leaf Distribution Company.

Beck, A. T., Epstein, N., Brown, G., & Steer, R. A.

(1988). An inventory for measuring clinical anxiety:

psychometric properties. J Consult Clin Psychol, 56(6),

The effect of a Bioenergy Economy Program Derakhshan et al.

Int J Body Mind Culture, Vol. 3, No. 1, 2016


-897. Retrieved from PM:3204199

Bell, I. R., Lewis, D. A., Brooks, A. J., Lewis, S.

E., & Schwartz, G. E. (2003). Gas discharge

visualization evaluation of ultramolecular doses of

homeopathic medicines under blinded, controlled

conditions. J Altern Complement Med, 9(1), 25-38.

doi:10.1089/107555303321222928 [doi]. Retrieved

from PM:12676033

Benson, H. (1976). The Relaxation Response .

Boston, MA: G. K. Hall.

Bigal, M. E., & Lipton, R. B. (2006). Modifiable

risk factors for migraine progression. Headache, 46(9),

-1343. doi:HED577 [pii];10.1111/j.1526-

2006.00577.x [doi]. Retrieved from


Birocco, N., Guillame, C., Storto, S., Ritorto, G.,

Catino, C., Gir, N. et al. (2012). The effects of Reiki

therapy on pain and anxiety in patients attending a day

oncology and infusion services unit. Am J Hosp

Palliat. Care, 29(4), 290-294. doi:1049909111420859

[pii];10.1177/1049909111420859 [doi]. Retrieved

from PM:21998438

Borsook, D., Maleki, N., Becerra, L., & McEwen,

B. (2012). Understanding migraine through the lens of

maladaptive stress responses: a model disease of

allostatic load. Neuron, 73(2), 219-234. doi:S0896-

(12)00025-6 [pii];10.1016/j.neuron.2012.01.001

[doi]. Retrieved from PM:22284178

Bowden, D., Goddard, L., & Gruzelier, J. (2011). A

randomised controlled single-blind trial of the efficacy

of reiki at benefitting mood and well-being.

Evid.Based.Complement Alternat.Med, 2011, 381862.

doi:10.1155/2011/381862 [doi]. Retrieved from


Bradley, W. G., Daroff, R. B., Fenichel, G. M., &

Jankovic, J. (2008). Neurology in Clinical Practice (5th

ed.). Philadelphia, PA: Elsevier.

Breslau, N., Chilcoat, H. D., & Andreski, P. (1996).

Further evidence on the link between migraine and

neuroticism. Neurology, 47(3), 663-667. Retrieved

from PM:8797461

Brown, H., Newman, C., Noad, R., & Weatherby,

S. (2012). Behavioural management of migraine. Ann

Indian Acad Neurol, 15(Suppl 1), S78-S82.

doi:10.4103/0972-2327.100018 [doi];AIAN-15-78

[pii]. Retrieved from PM:23024569

Clark, D. A., & Beck, A. T. (2010). Cognitive

Therapy of Anxiety Disorders: Science and Practice.

Ne York, NY: Guilford Press.

Coussons-Read, M. E., Okun, M. L., & Nettles, C.

D. (2007). Psychosocial stress increases inflammatory

markers and alters cytokine production across

pregnancy. Brain Behav Immun., 21(3), 343-350.


[pii];10.1016/j.bbi.2006.08.006 [doi]. Retrieved from


Crawford, S. E., Leaver, V. W., & Mahoney, S. D.

(2006). Using Reiki to decrease memory and behavior

problems in mild cognitive impairment and mild

Alzheimer's disease. J Altern Complement Med, 12(9),

-913. doi:10.1089/acm.2006.12.911 [doi].

Retrieved from PM:17109583

Drummond, P., & Passchier, D. (2006).

Psychologyical mechanisms of migraine . In Olesen J

(Ed.), The Headaches (3rd ed., pp. 385-92).

Philadelphia, PA: Lippincott Williams & Wilkins.

Duckro, P. N., Chibnall, J. T., & Tomazic, T. J.

(1995). Anger, depression, and disability: a path

analysis of relationships in a sample of chronic

posttraumatic headache patients. Headache, 35(1), 7-9.

Retrieved from PM:7868342

Ducros, A. (2006). Mechanisms and genetics of

migraine. CNS. Drugs, 20 Spec no.1, 1-11. Retrieved

from PM:16841522

Energy Medicine University [Online]. [cited 2012];

Available from: URL:


Fava, A., Pirritano, D., Consoli, D., Plastino, M.,

Casalinuovo, F., Cristofaro, S. et al. (2014). Chronic

migraine in women is associated with insulin

resistance: a cross-sectional study. Eur J Neurol, 21(2),

-272. doi:10.1111/ene.12289 [doi]. Retrieved from


Gallo, L. P. (2002). Energy Psychology in

Psychotherapy: A Comprehensive Source Book

(Norton Energy Psychology). New York, NY: W. W.

Norton & Company.

Geggus, P. (2004). Introduction to the concepts of

Zero Balancing. J Bodyw Mov Ther, 8(1), 58-71.

Gharraee, B. (2003). Review some of the cognitive

model of anxiety and depression in patients with

comorbid conditions. [dissertation]. Tehran, Iran:

Clinical Psychology, Iran's Institute of Psychiatry; 2003.

Ghorbani, A., & Chitsaz, A. (2011). Comparison of

validity and reliability of the Migraine disability

assessment (MIDAS) versus headache impact test

(HIT) in an Iranian population. Iran J Neurol, 10(3-4),

-42. Retrieved from PM:24250844

Goli, F. (2008). Clinical analysis of energyinformation

flow in therapist-client communication.

Iranian Journal of Higher Health, 7, 7-21.

Goli, F. (2010). Bioenergy Economy: A

Methodological Study on Bioenergy-Based Therapies.

Bloomington, IN: Xlibris Corporation LLC.

Gudmundsson, L. S., Aspelund, T., Scher, A. I.,

Thorgeirsson, G., Johannsson, M., Launer, L. J. et al.

(2009). C-reactive protein in migraine sufferers similar

to that of non-migraineurs: the Reykjavik Study.

Cephalalgia, 29(12), 1301-1310. doi:CHA1865

[pii];10.1111/j.1468-2982.2009.01865.x [doi].

Retrieved from PM:19438929

Guldiken, B., Guldiken, S., Demir, M., Turgut, N.,

Kabayel, L., Ozkan, H. et al. (2008). Insulin resistance

and high sensitivity C-reactive protein in migraine.

The effect of a Bioenergy Economy Program Derakhshan et al.

Int J Body Mind Culture, Vol. 3, No. 1, 2016 43


Can J Neurol Sci, 35(4), 448-451. Retrieved from


Hamer, M., Gibson, E. L., Vuononvirta, R.,

Williams, E., & Steptoe, A. (2006). Inflammatory and

hemostatic responses to repeated mental stress:

individual stability and habituation over time. Brain

Behav Immun., 20(5), 456-459. doi:S0889-

(06)00004-3 [pii];10.1016/j.bbi.2006.01.001 [doi].

Retrieved from PM:16488574

Herron-Marx, S., Price-Knol, F., Burden, B., &

Hicks, C. (2008). A Systematic Review of the Use of

Reiki in Health Care. Altern Complement Ther, 14(1),


Hodge, DR. (2007). A systematic review of the

empirical literature on intercessory prayer. Res Soc

Work Pract, 17(2), 174-187.

Holroyd, K. A. (2002). Assessment and

psychological management of recurrent headache

disorders. J Consult Clin Psychol, 70(3), 656-677.

Retrieved from PM:12090375

Holroyd, K., & Lipchik, G. (1999). Behavior therapy

for headache. The Clinical psychologist, 52, 3-6.

Hurwitz, W. (2001). Energy medicine. In Micozzi

MS (Ed.), Fundamentals of Complementary and

Alternative Medicine. London, UK: Churchill


Jain, S., & Mills, P. J. (2010). Biofield therapies:

helpful or full of hype? A best evidence synthesis. Int J

Behav Med, 17(1), 1-16. doi:10.1007/s12529-009-

-4 [doi]. Retrieved from PM:19856109

Katz, J., & Rosenbloom, B. N. (2015). The golden

anniversary of Melzack and Wall's gate control theory

of pain: Celebrating 50 years of pain research and

management. Pain Res Manag, 20(6), 285-286.

Retrieved from PM:26642069

Kaviani, H., & Mousavi, A. S. (2008). Psychometric

properties of the Persian version of Beck Anxiety

Inventory (BAI). Tehran Univ Med J, 66(2), 136-140.

Kosinski, M., Bayliss, M. S., Bjorner, J. B., Ware,

J. E. Jr, Garber, W. H., Batenhorst, A. et al. (2003). A

six-item short-form survey for measuring headache

impact: the HIT-6. Qual Life Res, 12(8), 963-974.

Retrieved from PM:14651415

Lee, M. S., Pittler, M. H., & Ernst, E. (2008).

Effects of reiki in clinical practice: a systematic review

of randomised clinical trials. Int J Clin Pract, 62(6),

-954. doi:IJCP1729 [pii];10.1111/j.1742-

2008.01729.x [doi]. Retrieved from


Levin, J., & Mead, L. (2008). Bioenergy healing: a

theoretical model and case series. Explore. (NY), 4(3),

-209. doi:S1550-8307(08)00070-0

[pii];10.1016/j.explore.2008.02.005 [doi]. Retrieved

from PM:18466852

Levor, R. M., Cohen, M. J., Naliboff, B. D.,

McArthur, D., & Heuser, G. (1986). Psychosocial

precursors and correlates of migraine headache. J

Consult Clin Psychol, 54(3), 347-353. Retrieved from


Lippi, G., Mattiuzzi, C., & Cervellin, G. (2014). Creactive

protein and migraine. Facts or speculations?

Clin Chem Lab Med, 52(9), 1265-1272.

doi:10.1515/cclm-2014-0011 [doi];/j/cclm.ahead-ofprint/

cclm-2014-0011/cclm-2014-0011.xml [pii].

Retrieved from PM:24717337

Lubeck, W. (2000). The Aura Healing Handbook.

New Delhi, India: Lotus Press.

Marcus, D. A. (2000). Identification of patients

with headache at risk of psychological distress.

Headache, 40(5), 373-376. doi:hed56 [pii]. Retrieved

from PM:10849031

Marcus, D. A., Blazek-O'Neill, B., & Kopar, J. L.

(2013). Symptomatic improvement reported after

receiving Reiki at a cancer infusion center. Am J Hosp

Palliat.Care, 30(2), 216-217. doi:1049909112469275

[pii];10.1177/1049909112469275 [doi]. Retrieved

from PM:23221065

Martin, MJ. (1985). Muscle contraction (tension)

headache. In Dorfman W & Cristofar L (Eds.),

Psychosomatic illness review (pp. 1-10). New York,

NY: Macmillan.

Materazzo, F., Cathcart, S., & Pritchard, D. (2000).

Anger, depression, and coping interactions in headache

activity and adjustment: a controlled study. J

Psychosom. Res, 49(1), 69-75.

doi:S0022399900001446 [pii]. Retrieved from


McEwen, B. S., & Seeman, T. (1999). Protective

and damaging effects of mediators of stress.

Elaborating and testing the concepts of allostasis and

allostatic load. Ann N Y Acad Sci, 896, 30-47.

Retrieved from PM:10681886

Melzack, R., & Katz, J. (2013). Pain. Wiley.

Interdiscip. Rev Cogn Sci, 4(1), 1-15.

doi:10.1002/wcs.1201 [doi]. Retrieved from


Melzack, R., & Wall, P. D. (1965). Pain

mechanisms: a new theory. Science, 150(3699), 971-

Retrieved from PM:5320816

Miller, G. E., Rohleder, N., Stetler, C., &

Kirschbaum, C. (2005). Clinical depression and

regulation of the inflammatory response during acute

stress. Psychosom. Med, 67(5), 679-687. doi:67/5/679

[pii];10.1097/01.psy.0000174172.82428.ce [doi].

Retrieved from PM:16204423

Minen, M. T., Begasse De, D. O., Kroon Van, D.

A., Powers, S., Schwedt, T. J., Lipton, R. et al. (2016).

Migraine and its psychiatric comorbidities. J Neurol

Neurosurg. Psychiatry, 87(7), 741-749. doi:jnnp-2015-

[pii];10.1136/jnnp-2015-312233 [doi].

Retrieved from PM:26733600

Murphy, M., & Donovan, S. (1997). The Physical

and Psychological Effects of Meditation: A Review of

Contemporary Research with a Comprehensive

The effect of a Bioenergy Economy Program Derakhshan et al.

Int J Body Mind Culture, Vol. 3, No. 1, 2016


Bibliography, 1931-1996. California, CA: Institute of

Noetic Sciences.

Nash, J. M., & Thebarge, R. W. (2006).

Understanding psychological stress, its biological

processes, and impact on primary headache. Headache,

(9), 1377-1386. doi:HED580 [pii];10.1111/j.1526-

2006.00580.x [doi]. Retrieved from


Nicholson, R. A., Houle, T. T., Rhudy, J. L., &

Norton, P. J. (2007). Psychological risk factors in

headache. Headache, 47(3), 413-426. doi:HED716

[pii];10.1111/j.1526-4610.2006.00716.x [doi].

Retrieved from PM:17371358

Nicholson, R. A., Buse, D. C., Andrasik, F., &

Lipton, R. B. (2011). Nonpharmacologic treatments for

migraine and tension-type headache: how to choose

and when to use. Curr Treat Options.Neurol, 13(1), 28-

doi:10.1007/s11940-010-0102-9 [doi]. Retrieved

from PM:21080124

Nijm, J., Kristenson, M., Olsson, A. G., &

Jonasson, L. (2007). Impaired cortisol response to

acute stressors in patients with coronary disease.

Implications for inflammatory activity. J Intern Med,

(3), 375-384. doi:JIM1817 [pii];10.1111/j.1365-

2007.01817.x [doi]. Retrieved from


O'Mathuna, D. P. (2000). Evidence-based practice

and reviews of therapeutic touch. J Nurs Scholarsh.,

(3), 279-285. Retrieved from PM:12462823

Olesen J., & Goadsby P. (2006). Synthesis of

migraine mechanisms. In Olesen, J., & Tfelt-Hansen,

P. (Eds.), The Headaches (pp. 393-398). Philadelphia,

PA: Lippincott Williams & Wilkins.

Olson, K., Hanson, J., & Michaud, M. (2003). A

phase II trial of Reiki for the management of pain in

advanced cancer patients. J Pain Symptom. Manage,

(5), 990-997. doi:S0885392403003348 [pii].

Retrieved from PM:14585550

Oschman, J. L. (2000). Energy Medicine: The

Scientific Basis. London, UK: Churchill Livingstone.

Marnie G. (2005). Translation of Psychological

Assessment. Trans. Pasha Sharifi H, Nikkho MR .

Tehran, Iran: Sokhan Publications .

Penzien, D. B., Andrasik, F., Freidenberg, B. M.,

Houle, T. T., Lake, A. E., III, Lipchik, G. L. et al.

(2005). Guidelines for trials of behavioral treatments

for recurrent headache, first edition: American

Headache Society Behavioral Clinical Trials

Workgroup. Headache, 45(Suppl 2), S110-S132.

doi:HED4502004 [pii];10.1111/j.1526-

2005.4502004.x [doi]. Retrieved from


Popper, K. R., & Eccles, J. C. (1977). The Self and

Its Brain: An Argument for Interactionism7.

London, UK: Routledge.

Radat, F. (2013). [Stress and migraine]. Rev Neurol

(Paris), 169(5), 406-412. doi:S0035-3787(13)00688-7

[pii];10.1016/j.neurol.2012.11.008 [doi]. Retrieved

from PM:23608071

Ranjit, N., Diez-Roux, A. V., Shea, S., Cushman,

M., Seeman, T., Jackson, S. A. et al. (2007).

Psychosocial factors and inflammation in the multiethnic

study of atherosclerosis. Arch Intern Med,

(2), 174-181. doi:167/2/174

[pii];10.1001/archinte.167.2.174 [doi]. Retrieved from


Rasmussen, B. K. (1993). Migraine and tensiontype

headache in a general population: precipitating

factors, female hormones, sleep pattern and relation to

lifestyle. Pain, 53(1), 65-72. doi:0304-3959(93)90057-

V [pii]. Retrieved from PM:8316392

Reich, W. (1974). The Function of the Orgasm;

Sex-economic Problems of Biological Energy. New

York, NY: Touchstone.

Shore, A. G. (2004). Long-term effects of energetic

healing on symptoms of psychological depression and

self-perceived stress. Altern Ther Health Med, 10(3),

-48. Retrieved from PM:15154152

Spierings, E. L., Ranke, A. H., & Honkoop, P. C.

(2001). Precipitating and aggravating factors of

migraine versus tension-type headache. Headache,

(6), 554-558. doi:hed01101 [pii]. Retrieved from


Staunton, T. (2002). Body Psychotherapy. Hove,

UK: Psychology Press.

Stein, D. (2000). Essential Reiki: A Complete

Guide to an Ancient Healing Art. New York, NY:

Crossing Press.

Tessitore, A., Russo, A., Esposito, F., Giordano, A.,

Taglialatela, G., De, M. R. et al. (2011). Interictal

cortical reorganization in episodic migraine without

aura: an event-related fMRI study during parametric

trigeminal nociceptive stimulation. Neurol Sci, 32

Suppl 1, S165-S167. doi:10.1007/s10072-011-0537-0

[doi]. Retrieved from PM:21533737

Tiller, W. A. (2002). The Real World of Modern

Science, Medicine, and Qigong. Bull Sci Technol Soc,

(5), 352-61.

Tshccannen, T. A., Duchro, P. N., & Wilson, J.

(2000). The role of anger and depression in recurrent

headache. Headache, 40, 373-6.

Venable, V. L., Carlson, C. R., & Wilson, J. (2001).

The role of anger and depression in recurrent headache.

Headache, 41 (1), 21-30. doi:hed01003 [pii]. Retrieved

from PM:11168600

Vitale, A. T., & O'Connor, P. C. (2006). The effect

of Reiki on pain and anxiety in women with abdominal

hysterectomies: a quasi-experimental pilot study.

Holist Nurs Pract, 20(6), 263-272. doi:00004650-

-00002 [pii]. Retrieved from PM:17099413

Waeber, C., & Moskowitz, M. A. (2005). Migraine

as an inflammatory disorder. Neurology, 64(10 Suppl

, S9-15. doi:64/10_suppl_2/S9 [pii]. Retrieved from


The effect of a Bioenergy Economy Program Derakhshan et al.

Int J Body Mind Culture, Vol. 3, No. 1, 2016 45


Wardell, D. W., & Engebretson, J. C. (2006).

Taxonomy of Spiritual Experiences. J Relig Health,

(2), 215-233.

Watson, L. (1999). Supernature. London, UK:

Coronet Books.

Weymouth, K, & Sandberg-Lewis, S. (2000).

Comparing the efficacy of healing touch and

chiropractic adjustment in treating chronic low back

pain: A pilot study. Healing Touch Newsletter, (3), 7-8.

Wilber, K. (1977). The Spectrum of Consciousness.

New York, NY: Theosophical Publishing House.

Winstead-Fry, P., & Kijek, J. (1999). An integrative

review and meta-analysis of therapeutic touch research.

Altern Ther Health Med, 5(6), 58-67. Retrieved from


Wium-Andersen, M. K., Orsted, D. D., Nielsen, S.

F., & Nordestgaard, B. G. (2013). Elevated C-reactive

protein levels, psychological distress, and depression in

, 131 individuals. JAMA Psychiatry, 70 (2), 176-184.

doi:1485898 [pii];10.1001/2013.jamapsychiatry.102

[doi]. Retrieved from PM:23266538

World Health Organization. (2011). Atlas of

Headache Disorders and Resources in the World 2011.

Geneva, Switzerland: World Health Organisation.

Yilmaz Avci, A., Lakadamyali, H., Arikan, S.,

Benli, U. S., & Kilinc, M. (2015). High sensitivity Creactive

protein and cerebral white matter

hyperintensities on magnetic resonance imaging in

migraine patients. J Headache Pain, 16, 9.

doi:10.1186/1129-2377-16-9 [doi];1129-2377-16-9

[pii]. Retrieved from PM:25595197

Zafarnia, N., Abbaszadeh, A., Borhani, F., Miri, S.,

& Soleimanian, L. (2010). The effect of Therapeutic

Touch on pre exam anxiety in Kerman University of

Medical Sciences Students. J Qual Res Health Sci, 9(1-

, 47-54.

Zolfaghari, M., & Hazrati, M. (2001). Survey effect

of energy therapy method on anxiety and incidence of

cardiac Dysrhythmia inpatients under cardiac

catheterization. Hayat, 7(1), 14-22