The Association of Psychological Comorbidity with the Number of Functional Gastrointestinal Disorders


  • Hamidreza Roohafza Assistant Professor, Cardiac Rehabilitation Research Center, Cardiovascular Research Institute, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
  • Ali Molaee Resident, Department of Psychiatry, Isfahan University of Medical Sciences, Isfahan, Iran
  • Hamid Afshar Associate Professor, Psychosomatic Research Center AND Department of Psychiatry, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  • Mina Mazaheri PhD Student, Psychosomatic Research Center AND Department of Psychiatry, School of Medicine‎, Isfahan University of Medical Sciences, Isfahan, Iran
  • Awat Feizi Associate Professor, Department of Biostatistics, School of Public Health, Isfahan University of Medical Sciences, Isfahan, Iran
  • Ammar Hassanzadeh-Keshteli Integrative Functional Gastroenterology Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
  • Peyman Adibi Professor, Integrative Functional Gastroenterology Research Center AND Department of Gastroenterology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran



Functional gastrointestinal disorders (FGIDs), Psychological disturbances, Rome III


Background: The overlap of functional gastrointestinal disorders (FGIDs) has been reported in literature. Hence, this study aimed to examine psychological comorbidity with the number of FGIDs.
Methods: A total of 4763 individuals in 20 cities across Isfahan Province, Iran, were selected through cluster random sampling. The Rome III questionnaire in its complete form was used to investigate gastrointestinal symptoms. The other data collection tools consisted of the Stressful Life Events (SLE) Questionnaire, and Hospital Anxiety and Depression Scale (HADS). To analyze the data, t-test, chi-square test, and logistic regression analyses were used.
Results: The results of logistic regression analysis showed that the number of functional gastrointestinal disorders was the risk factor for stress level, anxiety, and depression and increased the odds ratio (OR) of these disturbances.
Conclusion: Increase in the number of functional gastrointestinal disorders was associated with more psychological comorbidity. Therefore, overlap of functional gastrointestinal disorders functional gastrointestinal disorders to be carefully considered and physicians should pay more attention to psychological factors when FGIDs overlap.


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How to Cite

Roohafza, H., Molaee, A., Afshar, H., Mazaheri, M., Feizi, A., Hassanzadeh-Keshteli, A., & Adibi, P. (2016). The Association of Psychological Comorbidity with the Number of Functional Gastrointestinal Disorders. International Journal of Body, Mind and Culture, 3(1), 22-29.



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